Plant Systems Biology and Evolution
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Welcome to the Mutwil Lab!
​The Mutwil lab is located within the School of Biological Sciences at Nanyang Technological University, Singapore.
We use systems biology to elucidate the function of genes in the plant kingdom. Today, knowledge of gene function is mostly confined to Arabidopsis thaliana, the main model organism in plant research, which limits our understanding of the plant kingdom. To remedy this, we are characterising also other plant species in terms of genomics, gene expression, metabolomics and protein-protein interaction networks. Based on this biological data we can then predict gene function with state-of-the-art network ensemble methods and other dry-lab techniques. This knowledge is important to understand plants and to tailor them to our needs.

February update

8/2/2019

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The year of the pig started well!
  1. I am very proud to say that Camilla Ferrari, my Ph.D. student from Max Planck Institute of Molecular Plant Physiology, defended her Ph.D. thesis with a very strong magna cum laude. Congrats to Camilla!
  2. Camilla's Ph.D. work culminated in a publication in Nature Communications (please check out the publications section). Further congrats, Camilla!
  3. We have been successful in securing a Tier 2 grant to study the biosynthetic pathways of Hedyotis corymbosa, which as potent growth inhibition activity against several forms of cancer. We will sequence and assemble the genome, generate transcriptomic and metabolomic atlas and identify the active compound by a combination of biophysical and in vivo approaches. 
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    Contact

    Asst. Prof. Marek Mutwil
    School of Biological Sciences
    Nanyang Technological University
    60 Nanyang Drive, 02s-88h
    ​Singapore 637551
    ​Email: mutwil[at]ntu.edu.sg

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